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Hypomethylation induced by HHcy appears to contribute to lipid deposition in tissues

If pain persists despite appropriate analgesia, underlying causes should be investigated rather than simply increasing medication doses

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investigated for selective fat-mobilising effects independent of GH receptor signalling Cartilage & joint research Examined in chondrocyte models and osteoarthritis frameworks for anabolic effects on cartilage matrix synthesis Metabolic profile Investigated for absence of the hyperglycaemic and IGF-1-elevating effects associated with full-length hGH, making it a useful tool compound for isolating GHs metabolic effects Body composition models Studied in rodent obesity models for changes in fat mass, lean mass, and energy expenditure Clinical research history Progressed to early-phase human trials in Australia (2000s) for obesity and osteoarthritis indications