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What Is It

Permeant fluorescent probes visualize the activation of SARM1 and uncover an anti-neurodegenerative drug candidate

Specifications: Form: Lyophilised powder Unit Size: 10 mg Appearance: White to off-white solid Storage (unreconstituted): -20 C, dark, dry Reconstitution: Sterile bacteriostatic water Stability (reconstituted): Store at 28 C, short-term Usage Notice: For research use only

In the Phase 2 Lancet trial, orforglipron 45 mg reduced HbA1c by up to 2.1 percentage points at 26 weeks, exceeding the reduction achieved by dulaglutide 1.5 mg (the active comparator)