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Smoking should also be stopped prior to starting of clozapine.[] When the patient on medications which can potentially cause gastrointestinal hypomotility, bowel habits must be monitored by clinicians during all the follow-up visits and appropriate preventive measures must be ensured

The temperature of column oven was set at 40 C, and the injection volume was 1 L

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Informed consent All participants in this study were informed about the objectives of the study and the side effects of the dietary supplement used in the intervention