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[DOI] [PMC free article] [PubMed] [Google Scholar] 31

Der Rest bleibt im Darm und wird je nach Zusammensetzung der Darmflora zu anderen Produkten umgebaut, die nicht immer harmlos sind (zum Beispiel Trimethylamin-N-oxid)

The authors mutated residues in the orthosteric binding pocket of OR and tested the abilities of those mutants to activate G protein signaling and -arrestin recruitment by fentanyl, morphine, and DAMGO, respectively