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Low methionine intake (from animal products, nuts, and some legumes) or excess folate, B6, betaine, or N-acetylcysteine supplements can lower Hcy

An altered redox status in the PVAT in response to atherogenic factors, including obesity, hyperlipidemia, aging, and other stimuli, might signal to the surrounding vascular tissue and incline to the development of atherosclerosis (Xia et al., 2016