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To address the challenge of limited drug delivery to the ischemic region in stroke, researchers leveraged the inherent ability of macrophage membranes to penetrate the BBB

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We are finalizing with clarification our proposal to adjust the benchmark to account for the impact of improper payments, in the event CMS recalculates a payment determination and issues a revised initial determination for a performance year in a prior agreement period that corresponds to a benchmark year of the ACO's agreement period (emphasis added to reflect clarified text)