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Pharmacogenomics of the heptahelical receptor regulators G-protein-coupled receptor kinases and arrestins: the known and the unknown

While the kinetic rate constants could not be accurately determined for GLP-1 QMP, GLP-1 QMP/LX (0.2 nM) showed an almost 600-fold higher binding affinity compared to GLP-1 WT (Fig

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Summary of key findings: In vitro: reduced oxidative stress, improved cell function