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[19] identified ring finger protein 217 as a novel E3 ligase mediating the degradation of ferroportin (FPN), which controls iron output alone or together with hepcidin

[7] [29] Ketoconazole There are no adequate and well-controlled studies of ketoconazole use during human pregnancy to evaluate for a drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes

While in some studies the phosphorylation state of OR is clearly determined, in most of them and especially those using kinase inhibitors this major information is lacking

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