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Unpacking NNMTs Role Through its involvement in the methylation of nicotinamide, a type of vitamin B3, and its impact on fat cell metabolism, NNMT plays a crucial role in metabolism

Taurines protection against mitochondrial disease associated with MELAS syndrome involves its conjugation to the uridines of tRNALeu(UUR), needed to provide the right anticodon matching, and, if this conjugation ability is lost, important mitochondrial protein expression like that of ND5 and ND6 is also deregulated