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152 The cytosolic lncRNA P53RRA competitively inhibits the binding of Ras-GTPase-activating protein-binding protein 1 (G3BP1) to TP53, which causes TP53-mediated cell cycle arrest, apoptosis and ferroptosis

[PUBMED Abstract] Flaherty KT, Robert C, Hersey P, et al.: Improved survival with MEK inhibition in BRAF-mutated melanoma

found that different mutations in carcinogenic genes lead to differences in metabolic reprogramming in liver cancer, with the glucose uptake and catabolic metabolism of MYC-induced liver tumors significantly higher than those of MET-induced tumors (83)

instillation to vehicle, 0.2 g (low-dose) or 1.0 g (high-dose) of LPS once a week for four weeks (n = 3 mice/group)