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Description

NNMT (nicotinamide N-methyltransferase) is an enzyme in adipose tissue that depletes NAD+ and promotes fat storage

Researchers are investigating whether 5-Amino-1MQ can leverage these properties to positively influence metabolism

Theres also interest in its anti-aging benefits, since boosting NAD+ and improving metabolism can have broad positive effects on health

in Nature Medicine demonstrated that blocking NNMT in white adipose tissue increased energy expenditure, reduced fat mass, and improved insulin sensitivity in animal models even without changes in diet or activity (Kraus et al., Nature Medicine )