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The parameters for protein searching were set as follows: tryptic digestion with upto two missed cleavages, carbamidomethylation of cysteines as fixed modification, and oxidation of methionines and protein N-terminal acetylation as variable modifications

One study published in the Journal of Alternative and Complementary Medicine tracked the effects of oral glutathione supplements and found no significant changes in the biomarkers of oxidative stress (20)

Thus, NM plays a dual roleprotective in healthy neurons and potentially harmful when degraded or released extracellularly (266270)

14,64,65 Drug-induced AP and other risk factors, such as smoking, are receiving increasing attention