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(4) intervention duration was at least seven days (we considered RCTs as separate studies if they were with two or more eligible arms)

The levels of FC and AC were significantly increased at one and two month and the levels of TC were significantly increased at all observed points from baseline, while the AC/FC ratios remained unchanged

Future translational efforts should pursue several directions: first, conducting deep-phenotyping trials in biopsy-confirmed MASH patients, using positron emission tomography to quantify hepatic glucose uptake and correlating these findings with intrahepatic insulin signaling (e.g., p-AKT)