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Description

Its synergistic interaction with the FGF21 pathway enhances hepatic insulin sensitivity

doi: 10.3389/fncel.2016.00179 38

(2013) 4:e36

Furthermore, FMO3 has been shown to serve as a central regulator of tissue cholesterol balance and to be involved in insulin resistance and dyslipidemic changes in mouse models, suggesting the FMO3 and TMAO pathway as potential mediators of diabetes associated atherosclerosis 52,53