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10.1093/abbs/gmaa174 Summary Keywords rheumatoid arthritis (RA), IL-1, autoimmune diseases, cytokines, immunotherapy, monoclonal antibody Citation Wang K, Luo H, Liu L, Gao H, Song Y and Li D (2025) Blockade of IL-1 family cytokines in the treatment of rheumatoid arthritis

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129 However, according to the findings of a phase II randomized controlled trial (NCT01210911, ClinicalTrials.gov, 2021), the addition of a conventional antidiabetic dose of metformin to the gemcitabine plus erlotinib regimen demonstrated no survival benefit in patients with advanced pancreatic adenocarcinoma