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Qiu et al., 2022)

5.1 Chronic stress and hippocampal synaptic plasticity Synaptic plasticity refers to changes in synaptic structure and function in response to neuronal activity and serves as a fundamental neurobiological basis for learning and memory (Takeuchi et al., 2014)

found that FOXO1 represses the survival of osteosarcoma cells by inhibition of the Wnt/-catenin signaling, showing that the inhibition of Wnt/-catenin signaling by FOXOs is conserved during the development of bone and osseous tumorigenesis