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[PubMed: 15578035] 103

That triple mechanism produced the most dramatic weight reduction data in modern clinical trials, with participants losing up to 24.2% of their body weight over 48 weeks

Severe caloric restriction sometimes impairs concentration and mental clarity, likely due to low glucose availability and potential micronutrient deficiencies

It has been shown to promote gut health, reduce inflammation, and potentially address conditions like inflammatory bowel disease and leaky gut syndrome