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In general, oxidative stress and mitochondrial dysfunction in cardiomyocytes are believed to play pivotal roles in cocaine-induced cardiotoxicity 13,14,15,16,17

The document now includes all sections from the template with current evidence-based citations

In the early 20th century, Franz (1904) elucidated the mechanisms underlying FA degradation by successive cyclic removal of two carbon units at a time, which subsequently initiated further studies on FAO (Schlaepfer and Joshi, 2020)