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doi: 10.1021/jm300713s 148 LiaoWCHuangMZWangMLLinCJLuTLLoHRet al

The HGH alternatives guide compares peptide-based approaches against direct GH replacement

UXS1, UDP-xylose synthase

Loss of the NBS D nucleotide might be possible by the presence of a solvent accessible cavity that remains open toward NBS D even with interlocked NBDs in this conformation, whereas the tight interaction between the A-loop of CydC and ABC of CydD forms an enclosed inner environment for ATP around NBS C (Fig