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Recent studies on the antiviral effects of IRFs in HPV indicate that upregulation of these regulatory factors enhances the expression of IFNs and induces the immune clearance of HPV [71, 72]

Visomitin exhibited excellent renal protective effects in FA-, cisplatin-, and IR-induced models by reducing lipid peroxidation and mitochondrial ROS generation to ameliorate ferroptosis in kidneys in vivo and in vitro [189]

Although the mechanisms by which DUX4 exerts myotoxicity remain unclear, accumulating evidence has indicated that DUX4 induces oxidative stress, which plays an important role in FSHD pathogenesis (1, 2, 4, 14)