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Tissues with high metabolic activity would be predicted to produce higher levels of mitochondrial superoxide as a by-product of oxidative phosphorylation (Wallace, 2005) and be particularly subject to age-related disease

In addition, selenium helps to decrease nausea, diarrhea, and lymph retention in extremities that are caused by the adverse effects of cancer treatment (60)

The estimation of lipid peroxide along with superoxide dismutase & glutathione peroxidase in diabetes mellitus is very useful as it may serve as a useful monitor to judge the prognosis of the patients