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Epidermal fatty acid binding protein (E-FABP) expression in nave CD8+ T cells facilitates linoleic acid transport via mitochondria and its incorporation into cardiolipin, which induces lipid peroxidation and mitochondrial ROS production, leading to apoptosis and reduced TNF production [84]

Estrogen receptors and signaling in fibroids: role in pathobiology and therapeutic implications

This switch affects nearby neurons where the surge of lactate creates a rapid metabolic response in the neurons, with incoming lactate acting as an energy substrate, and depolarizing them to increase overall network excitability (Figure 2)

doi: 10.1186/1742-2094-8-63 92 PatelM