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This review has also proposed a mechanism of LC- and ALC-induced enhancement of female fertility, (a) directly by increasing energy production in oocytes and effectively quenching free radicals to provide protection against oxidative damage to the reproductive cells, and also (b) indirectly, by imposing their beneficial effects through HPG axis to ameliorate serum levels of hormones

At the initial baseline visit, serial venous sampling performed after oral d 3 -l-carnitine challenge revealed rapid increases in plasma concentrations of d 3 -l-carnitine, and subsequent increases in d 3 -BB and d 3 -TMAO following a lag phase (Figure 1, AC, filled circles)