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Macrophage-specific inhibition of NF-kappaB activation reduces foam-cell formation

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Thus, G6PD deficiency can cause the destruction of red blood cells through a build-up of oxidants in certain situations.[ref] NADPH is important in maintaining homeostasis in cells in several ways

Dihydrolipoic acid (DHLA), the reduced form of lipoic acid, restores these antioxidants by reducing their oxidized forms, maintaining redox balance through antioxidant regeneration