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10.1007/s00792-014-0716-z [DOI] [PMC free article] [PubMed] [Google Scholar] Jeyasingh PD, Goos JM, Thompson SK, Godwin CM, & Cotner JB (2017)

Elevated IGF-1 levels have been associated with increased risk of certain cancers, fluid retention, and joint pain

Song Y, Li J, Tian H et al (2023) Copper chelating peptides derived from tilapia ( Oreochromis niloticus ) skin as tyrosinase inhibitor: biological evaluation, in silico investigation and in vivo effects

23 Generally, alkaloids with pyrrolizidine, piperidine, tropane, and indolizidine in their chemical structures reportedly exhibit toxicity in humans and animals