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Selenium nanoparticles as neuroprotective agents: insights into molecular mechanisms for Parkinsons disease treatment

Under physiological pH, with the acid dissociation constant (pKa) being approximately 4.8, O 2 exists predominantly as an anion with limited membrane permeability, confining it largely to its site of generation

We concluded that SIRT7 phosphorylation by GSK3 enhances its ability to bind and stabilize SKP2, which is detrimental to the EGF-induced SKP2 protein turnover and subsequently compromises AKT activation

The result is a powerful skin resurfacing effect without the harsh thermal impact associated with older laser systems