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However, at present, a better understanding of the role of kynurenine pathway and other NAD biosynthetic pathways during HIV infection is needed to establish whether this population could benefit from niacin supplementation

& Schwartzberg, L

Nat Rev Endocrinol 8 , 160171 (2012)

Next, we detected the levels of DCFH-DA and found that, compared to control cells, the ROS levels were significantly higher in ACTL6A-KD cells with or without H 2 O 2 treatment (Fig