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doi: 10.1089/ars.2021.0072 33 ChenH.TengY.LiuZ.GengF.ChenX.JiangH.et al

Importantly, people who already have liver disease are at a higher risk of liver damage from acetaminophen because they likely arent producing enough glutathione

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S-nitrosothiols formed from the NO-dependent S-nitrosation of thiol-containing proteins and peptides such as albumin and glutathione are implicated in the in vivo transport, storage, and metabolism of NO