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Following OMM protein ubiquitination, TAX1BP1 is recruited to damaged mitochondria, where it interacts with LC3 via its LIR motif to initiate autophagosome formation and mitochondrial clearance (70)

Functional Metabolic Screen Identifies 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4 as an Important Regulator of Prostate Cancer Cell Survival