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Cho Y-T, Yang C-W, Chu C-Y

Novobiocin belongs to the class of aminocoumarin antibiotics, and it inhibits bacterial DNA gyrase 61

These findings demonstrate that primary canine hepatocytes are a viable model in which to study ITZ-associated hepatotoxicity in dogs

The UK Reference Nutrient Intake (RNI) for protein is 0.75g/kg/day for adults, though some expert bodies suggest higher intakes (1.0-1.2g/kg/day) may benefit older adults, particularly those who are active or frail