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41,42 Our findings establish lentiviral U7-snRNA-mediated exon skipping as a promising, mechanism-based therapeutic approach for NF1 -mutant BC and support its further development for genetically defined, treatment-refractory tumors

Wynne-EllisMMMursuJJTuomainenTPBertone-JohnsonESalonenJTVirtanenJKet al

Jones D, Carlson JL, Mody VC, Cai J, Lynn M, Sternberg P

Tanabe S, OBrien J, Tollefsen KE et al (2022) Reactive oxygen species in the adverse outcome pathway framework: toward creation of harmonized consensus key events