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Imaging data have so far provided evidence that clearly distinguishes depression from the other mood states in bipolar disorder

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El stress oxidativo puede ser causado por toxicidad de drogas, isquemia, metstasis, enfermedades cardiovasculares, neurodegenerativas, diabetes, radiaciones y procesos inflamatorios mediados por citoquinas, entre otros (9)(11-14)

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Cunard R, DiCampli D, Archer DC, Stevenson JL, Ricote M, Glass CK

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The upregulated urea cycle removes -amyloid and ammonia on one hand, while on the other, overproduction of the urea cycle metabolite ornithine leads to the overexpression of the enzyme ornithine decarboxylase 1 (ODC1), which produces excessive putrescine that subsequently degrades into GABA, H 2 O 2 and ammonium (see previous section)

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