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The review offers valuable insights into kombucha research, including substance metabolism and transformation, efficacy, pharmacological mechanism, and the purification of active components, offering direction and focus for further studies in this field

To achieve this, these enzymes can bind non-substrate ligands (ligandin function) and/or catalyze the conjugation of glutathione onto the targeted molecules, the latter activity being exhibited by GSTs having a serine or a tyrosine as catalytic residues

doi: 10.3748/wjg.v28.i23.2546 Summary Keywords diabetic kidney disease, gut microbiota, short-chain fatty acids (SCFAs), probiotics, fecal microbiota transplantation (FMT) Citation Wang X, Liu X, Gong F, Jiang Y, Zhang C, Zhou W and Zhang W (2025) Targeting gut microbiota for diabetic nephropathy treatment: probiotics, dietary interventions, and fecal microbiota transplantation