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Following energy deficit, lean body mass increased in Testosterone and remained stable in Placebo, such that lean body mass significantly differed between groups [mean difference between groups (95% CI), 2.5 kg (3.3, 1.6)

In fact, they could have completely normal methylation

doi: 10.3389/fimmu.2023.1228754 Received 25 May 2023 Accepted 18 July 2023 Published 09 August 2023 Volume 14 - 2023 Edited by Jian Shen, Shanghai Jiao Tong University, China Reviewed by Jinhui Li, Saint Louis University, United States