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Other symptoms The buildup of copper in other organs can cause: bluish discoloration in the nails kidney stones premature osteoporosis, or lack of bone density arthritis menstrual irregularities low blood pressure A mutation in the ATP7B gene, which codes for copper transportation, causes Wilsons disease

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Another option for vitamin B12 supply, which is given in particular in the case of a clinically manifest deficiency, is the parenteral form or vitamin B12 injections

The rising incidence of MI, the lack of effective pharmacological treatments for HF, and the emergence of various complications due to the side effects of chemical drugs present significant challenges