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The company positions the approach as a more accessible alternative for patients who are candidates for isotretinoin therapy but may be hesitant to pursue the oral formulation, including women of childbearing potential

Growth hormone, interferon-, and leukemia inhibitory factor utilize insulin receptor substrate-2 in intracellular signaling

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FK866 was again administered at a low dose (0.5 mg/Kg) to aged mouse models over four weeks, leading to significant improvements in cognitive function and locomotor activity