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Given this intrinsic resistance to ferroptosis, therapeutic strategies have been developed to pharmacologically bypass these cellular defenses

Apoptosis is one of the most extensively researched regulated cell death forms [4]

As a result of this, researchers need to be especially careful when handling reconstituted peptides compared to their lyophilized counterparts (Sigma-Aldrich, 2023a)

Furthermore, current understanding of the toxicological mechanism of action of THC components would not readily explain the observed higher association with maximum THC levels than median THC levels, particularly as there does not appear to be an attenuation of the effect during the 5-year follow up