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Ye H, Liu Y, Li N, Yu J, Cheng H, Li J, et al

Richardson DR, Lok HC (2008) The nitric oxide-iron interplay in mammalian cells: transport and storage of dinitrosyl iron complexes

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As with other substance use disorders, both genetic (such as mutations in the opioid receptor gene (10)) and environmental factors (such as exposure to trauma), contribute to the risk of developing opioid use disorder.(11) Ready access to prescription opioid, heroin, and fentanyl have all contributed to the current opioid epidemic