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Premedication and Concomitant Agents to Mitigate Toxicity: Vitamin supplementation: Start folic acid (400 to 1000 mcg orally once a day) 7 days before the first dose of this drug and continue until 21 days after the last dose of this drug

Radiation-induced kidney injury: A role for chronic oxidative stress

420 However, KD may contribute to decreased sensitivity to peripheral insulin and impaired glucose tolerance by upregulating insulin receptors, as determined by previous studies, which contradicts clinical findings