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Anisimov, Khavinson et al (2003, transgenic mice)

PDT can kill tumour cells but is limited by the low bioavailability of phototherapeutic agents

Candidates for iCRRT need to be carefully chosen so that this highly resource intensive therapy can be optimally deployed to benefit this fragile population

This "builds over time" narrative is community-reported and aligns loosely with the synaptogenesis framing, but it is anecdote layered on a mechanism story whose foundational papers were retracted