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Therefore, tumor-derived EVs are an ideal candidate for cell-free immunotherapeutic vaccines that can induce antitumor immunity and prevent tumor growth [261,262]

Illustratively, the assessment included the morphologic features of mucosal injury (i.e., different grades of epithelial lifting, villi denudation, and necrosis), inflammation (i.e., focal to diffuse, according to lamina propria infiltration or subendothelial infiltration), and hyperemia/hemorrhage (i.e., focal to diffuse, according to lamina propria or subendothelial localization)

10.1007/s00436-020-06968-x 164

Hydroxyurea attenuates oxidative, metabolic, and excitotoxic stress in rat hippocampal neurons and improves spatial memory in a mouse model of Alzheimer's disease