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Injections bypass the gut and deliver B12 directly into circulation, making them particularly effective in these cases

The authors reported that intra-articular AOD-9604 injection in the rabbit osteoarthritis model produced macroscopic, histologic, and biomechanical evidence of cartilage preservation relative to untreated controls, with the combination of AOD-9604 plus hyaluronic acid yielding the most consistent chondroprotective effect [4]

Additionally, DSIP may play a role in stress reduction, mood regulation, and pain management

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