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Safety monitoring is also crucial while probiotics and FMT have been safe in trials so far, there is a theoretical risk of introducing infections or causing undesired immune reactions, especially in patients with immune dysfunction (like those on MS immunosuppressants)

Pharmacologic inhibitors of SLC7A11 effectively induce tumor regression and abrogate MCU-driven metastasis in PDAC (Wang et al., 2022)

As a result, antiepileptic medication can be proposed to target HDAC1-3-mediated histone delactylation

However, a meta-analysis reported that the use of NAC showed no significant improvement in pregnancy rate, serum LH level, fasting insulin, and LH/follicle-stimulating hormone (FSH) ratio despite that the BMI and total testosterone were significantly reduced (138)