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On day 5 post-exposure, Nrf2-KO mice showed a transient increase in ABR thresholds, which returned to base-line by day 14

Capitalizing on the natural plaque-homing capability of platelets, this system achieved enhanced targeting towards atherosclerotic lesions, validating the ability of platelet-derived vesicles to effectively deliver therapeutic agents to the atherosclerotic lesion

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These include a low protein diet, low intake of sulfate rich foods, high toxin exposure (which depletes sulfate), low magnesium levels, low molybdenum levels, and issues with the sulfotransferase (SULTs) family of enzymes