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Oxidative stress can break down collagen, a structural protein that keeps your skin strong, elastic, and resilient

Important caveat: the human evidence base is thin and largely unreplicated outside the original Russian groups, and most data are preclinical or older clinical work without modern independent confirmation [13]

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Many of those studies demonstrated an acute beneficial effect, however, liver toxicity associate with frequent use of CGRP small molecule inhibitors has hampered progress