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Description

This three helix bundle domain has been used as a scaffold for the construction of combinatorial phagemid libraries, from which affibody variants that target the desired molecules can be selected using phage display technology see, e.g,

Other interesting experimental studies also confirmed that AFB1 is mainly bound to HSA in binding site I located in subdomain IIA with a binding affinity around 10 4 M 1 (177, 191)