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Dec 30, 2025 Danish pharmaceutical research produced tesofensine while searching for Alzheimer's and Parkinson's treatments in the early 2000s

The data on cat2 were compared with responses to external H 2 O 2 , ozone, and paraquat (Figure 4C) and to results obtained for the flu mutant, which generates excess singlet oxygen in the chloroplast (Figure 4D)

Wang JT, Medress ZA, Barres BA

Preclinical research suggests the compound enhanced neuronal survival and connectivity, and shows positive effects on oxidative stress, swelling, cell clean-up, blood-brain barrier integrity, and inflammation following brain injury, according to a corporate presentation