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The first incubation lasted 1 h, followed by the second incubation of 30 min

The following laboratory procedures of the quantification of targeted analytes were performed similarly to those in our previous study 11

We used a Decision Tree, Minimum Redundancy Maximum Relevance (MRMR), Elastic Net, and least absolute shrinkage and selection operator to refine the selection of important features

Together, these findings clearly indicate that inhibition of OXPHOS and active glycolysis might have been readily used for ATP synthesis by hyperplastic stromal tissue to maintain HOSC in a viable and proliferative state