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Telomeric repeat-containing RNA (TERRA) is transcribed from the d(TTAGGG) repeat sequence in mammalian telomeres

High voltage (2000 V) was applied to low volume Titanium union (Valco) and the tip positioned ~5 mm from the heated capillary ( T = 275 C) of an Orbitrap Fusion Lumos (Thermo Electron, Bremen, Germany) mass spectrometer