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2019 Oct;44(Suppl 1):S7780

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The peptides create several biological effects in cartilage tissue: They stimulate extracellular matrix macromolecule synthesis, including proteoglycans and type II collagen [3] They trigger chondrogenic proliferation and differentiation [3] They boost osteoblast activity while reducing osteoclast activity [3] These effects explain why collagen supplements protect cartilage in osteoarthritis and help repair it [3]